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Pages: 10
Size: 110 KB
Year: 2006
Price: Free

PRODRUGS Prodrugs

Carrier-linked prodrugs – drugs that are attached through a m etabolically labile chem ical linkage to another m olecule designated as the ______.
Pages: 131
Size: 717 KB
Year: 2007
Price: Free

Novel Prodrug Structures for Improved Drug Delivery

Oct 27, 2007 pharmaceutical properties of novel prodrug structures, including aqueous solubility
Pages: 131
Size: 717 KB
Year: 2007
Price: Free

Novel Prodrug Structures for Improved Drug Delivery

Oct 27, 2007 pharmaceutical properties of novel prodrug structures, including the synthesis
Pages: 159
Size: 736 KB
Year: 2006
Price: Free

PRODRUG STRATEGIES AIMED AT IMPROVING TOPICAL

. Implications of NArNAOCAM-carboxylic acid Hydrolysis on Prodrug.
Pages: 16
Size: 292 KB
Year: 2008
Price: Free

Prodrug Designing of NSAIDs - ResearchGate

The prodrug designing is one of the several strategies used to overcome this In this paper, a
Pages: 14
Size: 167 KB
Year: 2007
Price: Free

A Water-Soluble Propofol Prodrug

pofol is cleaved by alkaline phosphatase to phosphate, formaldehyde and propofol. Formaldehyde is rapidly metabolised to formate. Although a formate 
Pages: 4
Size: 1006 KB
Year: 2005
Price: Free

Prodrug activation via catalytic antibodies

Proc. Natl. Acad. Sci. USA. Vol. 90, pp. 5337-5340, June 1993. Chemistry. Prodrug activation via
Pages: 4
Size: 404 KB
Year: 2000
Price: Free

COMPUTER-AIDED PREDICTION OF PRODRUG

multaneously predicting more than 100 types of pharma- cological Examples of Prognosis of the Main Activity Type for Prodrugs and the Corresponding Drugs.
Pages: 198
Size: 9.39 MB
Year: 2001
Price: Free

A STUDY OF DT-DIAPHORASE AS A PRODRUG-ACTIVATING

It has a dual role both as a prodrug-activating enzyme and as a protector in on his insighrfùl
Pages: 125
Size: 2.84 MB
Year: 2011
Price: Free

optimizing the enzyme/prodrug axis of suicide gene therapy using

prodrug must elicit a robust bystander effect, preferably by intracellular . dFdCDP acts as a
Pages: 27
Size: 299 KB
Year: 2011
Price: Free

ADC and prodrug linker - Annova Chem Inc.

Annova Chem Product - ADCs and Prodrug Linker Catalog_# CAS_RN Chemical_Name FW Formula LC0001
Pages: 29
Size: 165 KB
Year: 2008
Price: Free

Prodrugs for Amines

Mar 3, 2008 amide prodrugs that release, in vivo, the parent amine [21] A group at the Pasteur Institute later speculated that the azo link might not be 
Pages: 23
Size: 292 KB
Year: 2010
Price: Free

Prodrug Approach for Increasing Cellular Glutathione - MDPI.com

Mar 3, 2010 Once intracellular GSH is produced, some of it is delivered to specific to GSH by NADPH-dependent glutathione reductase (GR) (Figure 1).
Pages: 15
Size: 789 KB
Year: 2008
Price: Free

Site-Specific Prodrug Release Using Visible Light

Site-Specific Prodrug Release Using . Visible Light. Michael Y. Jiang and David Dolphin* J. Am
Pages: 12
Size: 148 KB
Year: 2001
Price: Free

Strategies for Enzyme/Prodrug Cancer Therapy

Minireview Strategies for Enzyme/Prodrug Cancer Therapy1 Guang Xu and Howard L. McLeod2 Washington
Pages: 12
Size: 1.75 MB
Year: 2013
Price: Free

Targeted Polysaccharide Nanoparticle for Adamplatin Prodrug

Nov 19, 2013 targeted delivery, biocompatibility and biodegradability, and simplified delivery anticancer drugs and prodrugs, such as adamplatin, are.
Pages: 11
Size: 450 KB
Year: 2011
Price: Free

Glucuronidation of Anticancer Prodrug PR-104A: Species

clinical trial as a hypoxia- and aldo-keto reductase 1C3. (AKR1C3)-activated prodrug . tive
Pages: 9
Size: 141 KB
Year: 2005
Price: Free

Prodrug-Oriented Molecular Design of Neonicotinoids: Preparation

Prodrug-Oriented Molecular Design of Neonicotinoids: Preparation of Imidacloprid-Related 5,5
Pages: 9
Size: 3.83 MB
Year: 2011
Price: Free

Acid-Activatable Prodrug Nanogels for Efficient Intracellular

release in cancer cells. DOX prodrugs with drug grafting contents of 3.9, 5.7, and 11.7 wt % (denoted as prodrugs 1, 2, and 3, respectively) were
Pages: 9
Size: 199 KB
Year: 2001
Price: Free

Glucuronidation of Prodrug Reactive Site - Clinical Chemistry

clude prodrug forms of platelet-activating factor antago- nists (1), antiviral .. cleotide
Pages: 7
Size: 302 KB
Year: 2005
Price: Free

BETAMETHASONE PHARMACOKINETICS AFTER TWO PRODRUG FORMULATIONS IN

BETAMETHASONE PHARMACOKINETICS AFTER TWO PRODRUG FORMULATIONS IN SHEEP: IMPLICATIONS FOR ANTENATAL
Pages: 7
Size: 967 KB
Year: 2005
Price: Free

Phase IStudy oftheOrally Administered Butyrate Prodrug, Tributyrin

Butyrates induce reversible growth inhibition orterminal differentiation inawide variety ofcell lines vitro (7.8).They have produced cell death incertain human
Pages: 6
Size: 1.15 MB
Year: 2013
Price: Free

Review/Preview: Prodrug Ionic Liquids - ResearchGate

Ionic liquids; prodrugs; active pharmaceutical ingredients; pure liquid salts .. targeted delivery towards better ADME properties, Edited by. Mannhold R.
Pages: 8
Size: 243 KB
Year: 2004
Price: Free

camptothecin prodrugs

doi:10.1016/j.bmc.2004.01.039. Bioorganic & Medicinal Chemistry 12 (2004) Π– Π. Keywords: Prodrug
Pages: 60
Size: 513 KB
Year: 2007
Price: Free

Preclinical Studies of the Melphalan Prodrug J1 for Cancer - DiVA

Nov 30, 2007 combinations, co-drugs and prodrugs with melphalan as an exam- with a more general protease-inhibiting cocktail, indicating that amin-.
Pages: 2
Size: 2.53 MB
Year: 2011
Price: Free

Prodrug form for improved solubility & bioavailability of

Prodrug form for improved solubility & bioavailability of therapeutic agents Technology Offering
Pages: 2
Size: 106 KB
Year: 2001
Price: Free

Prodrug Metabolites: Implications for Therapeutic Drug Monitoring

Prodrug Metabolites: Implications for Therapeutic Drug Monitoring Prodrugs are analogs of active
Pages: 2
Size: 49 KB
Year: 2012
Price: Free

Site-Specific Prodrug Release Using Visible Light

backbone are barely changed as the photooxygenation took place Scheme 1. General Diagram of Drug Incorporation and Release Scheme 2.
Pages: 5
Size: 1.45 MB
Year: 2004
Price: Free

--"'" Adenoviral Thymidine Kinase Prodrug Gene Therapy Inhibits

This prodrug gene therapy strategy warrants investiga- tion as an adjuvant .. J. C., Amin, K. M
Pages: 41
Size: 1.22 MB
Year: 2013
Price: Free

A FtsZ-Targeting Prodrug with Oral Antistaphylococcal Efficacy In Vivo

Sep 16, 2013 physiological pH (7.4), TXY436 acts as a prodrug, converting to Huang, Q., F